Search results for "ISM [X-ray]"

showing 10 items of 1056 documents

Influence of Social Media on Corporate Heritage Tourism Brand

2017

Heritage tourism is an established research canon. However, corporate heritage tourism is an emerging research stream that integrates the heritage tourism canon and corporate brand attributes. This study, utilising a conceptual approach and proposing a conceptual model, explicates the role of social media (marketer and consumer-generated media) in fostering a sense of community among the corporate heritage tourism brand adherents and visit intention among members of the community. In addition, this study incorporates social identity theory to dilate group dynamics and to foster strong feelings and sense of identity among its community. peerReviewed

business.industryTourism geography05 social sciencesSense of communityHeritage tourismcorporate brandsosiaalinen mediaPublic relationsBrand managementCorporate brandingheritage tourism0502 economics and business050211 marketingSocial mediaBrand equitybusinessSocial identity theory050212 sport leisure & tourism
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Sport and Quality of Life

2022

Negli ultimi trent’anni lo sport ha assunto un significato molto rilevante nella vita delle persone e, seppure con notevoli differenze, sia nei paesi a sviluppo economico avanzato, sia in quelli in via di sviluppo. A livello individuale, esso ha costituito un’area di investimento identitario quando ha assunto la forma di sport spettacolo del quale fruire, alimentando la pratica del tifo e il fandom o costituendo il modello di uno stile di vita vincente; ma anche quando ha assunto la forma di pratica del tempo libero attraverso la quale tenersi in forma, facendo crescere, in questo caso, la diffusione di una cultura della salute e del benessere. Si tratta di due modalità di approcciare al co…

but also when he took the form of free time practice through which to keep fit making grow in this case the diffusion of a culture of health and well-being. These are two ways of approaching the consumption of sports by spectators and actorIn the last thirty years sport has taken on a very significant meaning in people's lives and albeit with considerable differences both in advanced economic development countries and in developing countries. On an individual level it constituted an area of identity investment when it assumed the shape of “sport spectacle” to be enjoyed fueling the practice of cheering and fandom or constituting the model of a winning lifestyleand the two ways of use can be strongly related to the perception and assessment of the quality of life. The “semantic universes” which however connote sport and “free time sports” have often appeared polarized. Commercial sport and sports professionalism are intertwined with the institutions of economics politics and culture which above all stress its “spectacularity” in order to capture first and foremost the audience. But also the sport of leisure time is intertwined with the actions of the institutions of economics politics and culture with the difference that these stress above all its “healthy value” aimed at the “healthy and rational” investment of time in an activity which improves the quality of life in the short medium and long period. This polarization between the consumption of sport entertainment - commercial sport - and the consumption of sport as a leisure activity - sport for all - has become increasingly interconnected precisely because of the increased collective identity demand via sport. In other words we have witnessed the spread of shape of sports entertainment that recall the importance of sports for psychophysical well-being for integration and social participation for the reduction of social inequalities ethnic and cultural differences and in which the importance assumed was weakened in the show from agonism from competition from the physical confrontation between two contenders or two teams. A sport in which we act with competitors as well as against competitors. And on the other hand we have gradually witnessed the spectacularization of sports in our free time to the point that the sharing of the results obtained through the declination of a competitive spirit that presents itself as directed no longer against other contenders but against its own performance limits it has become the way in which each person makes part of his or her own life spectacular the one he often considers most authentic. The aim of this work is to describe how the intertwining between the commercial/professional dimension of the sports show and the playful/recreational dimension of sports practice are fueled by a demand and an offer of social identity that characterizes these two “semantic universes”.Settore SPS/07 - Sociologia Generale
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La dialèctica corpus/estatus en la història de la llengua catalana. Cap a una explicació integral dels canvis lingüístics

2021

En aquest article advoquem per la superació de les dicotomies que parcel·len l’estudi dels fets de llengua (sincronia vs. diacronia, lingüística vs. sociolingüística, història interna vs. història externa), en pro d’un atansament que integri el màxim nombre de factors explicatius possibles. Un àmbit propici per a aquesta confluència és l’anàlisi dels canvis lingüístics en curs, que són aquells que tenen lloc en temps real davant dels ulls de l’investigador, el qual es pot beneficiar així de la proximitat a l’objecte d’estudi i de l’accessibilitat als múltiples factors que en condicionen l’evolució, sempre que sigui capaç de no implicar-s’hi en excés. L’anàlisi de les transformacions que s’o…

catalan and spanish“UNESCO:CIENCIAS DE LAS ARTES Y LAS LETRAS”Linguistics and Languageideologies mediàtiquesllengua i ideologiaPhilosophymedia ideologybilingüisme i llengua catalanaLanguage and LinguisticsLanguage planningsovereignty processbilingualism and catalanprocés sobiranistaHumanitiescatalà i castellàlanguage and ideologyCaplletra. Revista Internacional de Filologia
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A synthetic hexapeptide (Argireline) with antiwrinkle activity

2008

Botulinum neurotoxins (BoNTs) represent a revolution in cosmetic science because of their remarkable and long-lasting antiwrinkle activity. However, their high neurotoxicity seriously limits their use. Thus, there is a need to design and validate non-toxic molecules that mimic the action of BoNTs. The hexapeptide Ac-EEMQRR-NH2 (coined Argireline) was identified as a result of a rational design programme. Noteworthy, skin topography analysis of an oil/water (O/W) emulsion containing 10% of the hexapeptide on healthy women volunteers reduced wrinkle depth up to 30% upon 30 days treatment. Analysis of the mechanism of action showed that Argireline significantly inhibited neurotransmitter relea…

chemistry.chemical_classificationAgingRational designNeurotoxicityPharmaceutical SciencePeptideDermatologymedicine.diseaseExocytosisColloid and Surface ChemistryMechanism of actionchemistryBiochemistryChemistry (miscellaneous)In vivoDrug DiscoveryToxicitymedicineNeurotoxinmedicine.symptomInternational Journal of Cosmetic Science
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Sequiterpene-related compounds as endocrine disrupters in Oncopeltus fasciatus, and potential reduced glutathione synthesis modifiers

1999

Sesquiterpene lactones have been found to exhibit effects on insect growth and development. In this study, the bioactivity of natural lactones extracted from Centaurea mariolensis and some structurally related synthetic derivatives has been investigated. Assays have also been carried out in order to determine the potential of these lactones as modifiers of reduced glutathione (GSH) synthesis.

chemistry.chemical_classificationEnvironmental EngineeringChemical compoundStereochemistryChemical structureBiological activityGlutathioneBiologySesquiterpenePollutionchemistry.chemical_compoundMechanism of actionchemistryBiochemistryEndocrine disruptormedicineEnvironmental Chemistrymedicine.symptomWaste Management and DisposalLactoneScience of The Total Environment
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Bioactivation of the Fungal Phytotoxin 2,5-Anhydro-D-glucitol by Glycolytic Enzymesisan Essential Component of itsMechanism of Action

2002

An isolate of Fusarium solani, NRRL 18883, produces the natural phytotoxin 2,5-anhydro-ᴅ-glucitol (AhG). This fungal metabolite inhibited the growth of roots (I50 of 1.6 mᴍ), butit did nothave any in vitro inhibitory activity. The mechanism of action of AhG requires enzymatic phosphorylation by plant glycolytic kinases to yield AhG-1,6-bisphosphate (AhG-1,6- bisP), an inhibitor of Fru-1,6-bisP aldolase. AhG-1,6-bisP had an I50 value of 570 μᴍ on aldolase activity, and it competed with Fru-1,6-bisP for the catalytic site on the enzyme, with a Ki value of 103 μᴍ. The hydroxyl group on the anomeric carbon of Fru-1,6-bisP is required for the formation of an essential covalent bond to ζ amino fu…

chemistry.chemical_classificationStereochemistryLysineAldolase AFructose-bisphosphate aldolaseFructoseBiologyGeneral Biochemistry Genetics and Molecular BiologyMetabolic pathwaychemistry.chemical_compoundEnzymeMechanism of actionBiochemistrychemistrymedicinebiology.proteinmedicine.symptomBinding siteZeitschrift für Naturforschung C
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Plant-growth-regulating phosphono peptides

1990

Phosphono peptides exhibited plant‐growth‐regulating activity when tested on Lepidium sativum and Cucumis sativus. The studies have provided evidence that the mechanism of action of these compounds may involve the uptake of the phosphono peptides into the plant, intracellular hydrolysis of the peptide bond and release of the P‐terminal aminoalkylphosphonic acid. This acid or its metabolite is then probably responsible for the observed physiological effect.

chemistry.chemical_classificationStereochemistryMetabolitefood and beveragesPeptideBiological activityApplied Microbiology and BiotechnologyLepidium sativumHydrolysischemistry.chemical_compoundchemistryBiochemistryMechanism of actionmedicinePeptide bondmedicine.symptomIntracellularPesticide Science
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Mode of action of herbicidal derivatives of aminomethylenebisphosphonic acid. Part II. Reversal of herbicidal action by aromatic amino acids

1997

The herbicidal action of N-pyridylaminomethylenebisphosphonic acids is accompanied by an impairment of anthocyanin biosynthesis. This suggests that they might act as inhibitors of some steps in aromatic amino acid biosynthesis. Herbicidal effects were reversed by aromatic amino acids using both bacterial and plant models, a finding that strongly supports this hypothesis. Structural features of these compounds suggest the sixth enzyme in the shikimate pathway 5-enol-pyruvoylshikimate-3-phosphate (EPSP) synthase as a possible target, since a strong structural similarity exists between aminomethylenebisphosphonic acid and an inhibitor of EPSP synthase, the herbicide glyphosate. This is, howeve…

chemistry.chemical_classificationaromatic metabolismStereochemistryN-Pyridylaminomethylenebisphosphonic acids; EPSP synthase; Herbicides; Glyphosate; Aromatic metabolismEPSP synthasePlant Science3-Phosphoshikimate 1-Carboxyvinyltransferasechemistry.chemical_compoundEnzymeherbicidesBiochemistrychemistryMechanism of actionBiosynthesisN-Pyridylaminomethylenebisphosphonic acidsglyphosatemedicineAromatic amino acidsShikimate pathwaymedicine.symptomMode of actionAgronomy and Crop ScienceEPSP synthaseJournal of Plant Growth Regulation
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The Mechanism of Action of Carbonic Anhydrase

1990

A survey of the structure-function relationship in the enzyme carbonic anhydrase is presented. The coordination number around the metal ion in derivatives inhibited with some anions is stressed as well as the role of the cavity in determining the coordination number. Inferences on the enzyme-substrate interactions are presented.

chemistry.chemical_classificationbiologyChemistryCoordination numberCombinatorial chemistryMetalEnzymeMechanism of actionvisual_artCarbonic anhydrasemedicinevisual_art.visual_art_mediumbiology.proteinmedicine.symptom
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Mechanisms of photosensitization by drugs: Involvement of tyrosines in the photomodification of proteins mediated by tiaprofenic acid in vitro

1997

The photosensitizing potential of drugs must be related to their photoreactivity towards the target biomolecules. In this context, a representative photosensitizing drug (tiaprofenic acid) was co-irradiated with a model protein, bovine serum albumin (BSA). This led to a significant degree of protein crosslinking and to the formation of trace amounts of drug-BSA photoadducts. Amino acid analysis of the hydrolysed (HC1) protein showed that His and Tyr undergo a dramatic decrease (approx. 90%) as a consequence of drug-mediated photodynamic processes. When the drug was irradiated in the presence of the pure amino acids, extensive phototransformation of the latter was observed. Other photosensit…

chemistry.chemical_classificationbiologyChemistrySerum albuminContext (language use)General MedicineToxicologyAmino acidMechanism of actionBiochemistrymedicinebiology.proteinmedicine.symptomTyrosineBovine serum albuminTiaprofenic acidHistidinemedicine.drugToxicology in Vitro
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